CBG oil, also known as cannabigerol, is one of the several compounds present in cannabis plants. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two most well-known cannabinoids, although there has recently been increased interest in the possible advantages of CBG.
It is thought that CBG came before other cannabinoids. It is because when heated, CBG-A, the acidic form of CBG, decomposes to produce THC, CBD, CBG, and CBC (cannabichromene), another cannabinoid.
What Is CBG Oil?
CBG, often referred to by experts as "the mother of all cannabinoids," is the cannabinoid from which other types of cannabinoids (CBD) are derived, says Michelle Sexton, a naturopathic doctor at the Pain Trauma Institute in San Diego. "CBG is the first compound in the biosynthesis (the production of chemical mixtures by a living organism) of the other cannabinoids," she adds.
Since Cannabis oil and cancer, CBG is a starting compound in the cannabis plant; young marijuana plants are usually used to obtain the cannabinoid because when the plant is mature, there is not much CBG left. Instead, the plant is more abundant in THC and CBD, according to Dr. Sexton. Young cannabis plants contain cannabigerolic acid (CBGA), an acidic form of CBG, and as the plant grows, CBGA is naturally converted to CBDA and THCA, which can then be converted to CBD and THC when activated by the heat, the explains.
CBG is available in many forms, including tinctures, gummies, capsules, topical creams, and lotions. CBG is often combined with CBD in these products because the two cannabinoids can provide complementary benefits, such as decreasing inflammation and pain, says Fraser Smith, a naturopathic physician and assistant dean and associate professor at the National University of Health Services. Health in Lombard, Illinois.
How does CBG Work?
The body uses its endocannabinoid system to metabolize CBG. Regardless of our external environment, the chemicals and receptors that make up the endocannabinoid system maintain our bodies in an ideal state.
CBG mimics endocannabinoids, which are organic substances that our bodies naturally produce. However, it lacks the psychoactive effects of THC, so it won't make you feel high.
What are the Potential Benefits?
While the research on CBG is limited, studies do suggest that it offers several benefits.
CBG coconut oil may be able to improve the following health conditions:
- Inflammatory bowel condition: A 2013 study on mice suggested that CBG may help lower the inflammation linked to inflammatory bowel disease (Trusted Source).
- Glaucoma: Glaucoma appears to respond well to medical cannabis, and CBG may play a role in this. According to a 2008 Trusted Source study, CBG lowers intraocular pressure, which may make it useful in the treatment of glaucoma.
- Bladder dysfunctions: Certain cannabinoids appear to impact bladder contractions. According to a 2015 study (Trusted Source), CBG has the greatest potential for treating bladder dysfunctions after examining the effects of five different cannabinoids on the bladder.
- Huntington's disease: According to a 2015 study that examined animals with Huntington's disease, a neurodegenerative disorder, CBG may have neuroprotective qualities. The study concluded that CBG might be useful in the treatment of further neurodegenerative diseases.
- Bacterial infections: According to a 2008 investigation by a reliable source, CBG can eradicate bacteria, specifically the drug-resistant staph infection-causing methicillin-resistant Staphylococcus aureus (MRSA). These infections can be serious and difficult to treat.
- Cancer: A 2014 investigation. After examining colon cancer in rats, Reliable Source concluded that CBG may slow the growth of cancer cells and other cancers.
- Appetite loss: A 2016 rat study According to a reliable source, CBG may increase appetite. Chemicals that stimulate appetite could be utilized to aid those suffering from diseases like cancer or HIV.
Though encouraging, it's crucial to remember that these studies do not support CBG's advantages. An in-depth study is required to comprehend CBG's physiological effects completely.
Choosing a CBG Product
Because CBG oil is more difficult to get than CBD, finding a decent one can be challenging. Additionally, the Drug Administration (FDA) and Food do not regulate either CBD or CBG, so you will need to conduct additional research to be sure you are purchasing a high-quality product.
Here are a few Pointers to help get you Started
Try Full-spectrum CBD
Products with full-spectrum CBD contain trace amounts of several other cannabinoids. Plus, they're far easier to locate than those limited to CBG.
Furthermore, it's thought that taking all of the cannabinoids at once maximizes their effects.
See our list of suggested full-spectrum CBD oils.
Check for Third-party Testing
Products made by companies that use CBG should undergo testing by an impartial laboratory. Check if the company's goods have undergone third-party testing before purchasing CBG, and make sure to read the lab report, which should be sent to you via email or on the company's website.
CBG Concentration in Plants
Young cannabis plants contain higher concentrations of this cannabinoid than mature plants, which is why they are used to make CBG. Beginning as CBGA, an acidic version of CBG, CBD and THC are similar.
On the contrary, fully grown plants with high concentrations of THC and CBD have very low concentrations of CBG. In most plant varieties, only 1% of CBG can be found.1 This happens because most of the CBG has already been converted as the plant develops.
Some cannabis strains have a higher CBG content due to their genetic and biochemical makeup.2 Due to the difficulty in obtaining CBG, cannabis growers have been experimenting with crossbreeding and genetic manipulation to help cannabis plants deliver more of this cannabinoid.
Potential Benefits of CBG | CBG Oil Benefits
Studies indicate that CBG might have therapeutic benefits. Here are some of their findings, although additional research is required to determine the precise effects and potential advantages of this cannabinoid.
Anxiety and Depression
According to a small-scale study, the primary reason individuals used cannabis preparations high in CBG was to lessen anxiety, and one in three also reported using it to help with depression.4 According to the majority of users, CBG seemed to work better for these conditions than traditional medications.
Inflammatory Bowel Disease (IBD)
A review found that 15% to 40% of patients with (IBD) inflammatory bowel disease use cannabis and cannabinoids to both relieve pain and boost appetite. Six Researchers noted that while studies have indicated promise for its effects on IBD, there is a lack of high-quality evidence and guidance about the appropriate amount and manner of administration.
Glaucoma is more likely to develop in those with high intraocular pressure (IOP), sometimes referred to as eye pressure. The effect of cannabis on IOP has been the subject of numerous investigations. There is hope for treating glaucoma because many have discovered that these cannabis derivatives can lower intraocular pressure in both humans and animals.
The brain's nerve cells die down as a result of Huntington's disease. In addition to shielding some cells (N2a cells) from the harmful effects of excitatory neurotransmitters that, when activated for an extended period, cause cell death, cannabigerol also seems to have a favorable effect on cell viability.
According to a 2021 meta-analysis, CBG may also eliminate the inflammatory cells linked to breast cancer and appear to prevent the cancer cells from proliferating. Meta-analysis of breast cancer tissue cells' cannabigerol effects. Northern Colorado University.
Side Effects of CBG Oil for Anxiety
Some people experience side effects when taking CBG oil for anxiety, with some of the most common being:
- Dry mouth
- Dry eyes
- Increased appetite
Although there is a growing body of research on the possible negative effects and drug interaction concerns of CBG and other cannabinoids, not enough work has been done to make any firm conclusions.
One kind of cannabinoid present in the cannabis plant is cannabigerol (CBG). It is frequently called the "mother of all cannabinoids." The reason for this is that cannabigerolic acid (CBGA), an acidic version of CBG, is the source of other cannabinoids.
Vijaya Oil, CBG coconut oil, is found in lower amounts than other cannabinoids in cannabis plants, such as tetrahydrocannabinol (THC) and cannabidiol (CBD). It makes consumer products derived from cannabigerol rare and often expensive. However, CBG is gaining popularity due to the numerous potential benefits the cannabinoid presents.
The Most Important Thing to Know About CBG Oil for Sleep
Despite the fact that CBG is derived from plants, there is still much to learn about the advantages and disadvantages of using it. Marijuana is also highly addictive, so taking it for its possible CBG oil benefits could backfire.
Cannabinoid Receptors in the Body
Our body contains two types of cannabinoid receptors: CB1 and CB2. CB1 receptors are found in the anxious system and brain, while CB2 receptors are found in the immune system and other areas of the body.
CBG oil for pain works by binding to both receptors, where it is believed to strengthen the function of anandamide. Anandamide is one of the many neurotransmitters in the brain. It enhances pleasure and motivation, regulates appetite and CBG oil for sleep, and relieves pain.
What Dosage of CBD Should You Take?
Anxiety and Depression
According to a small-scale study, the primary reason individuals used cannabis preparations high in CBG was to lessen anxiety, and one in three also reported using it to help with depression. According to the majority of users, CBG seemed to work better for these conditions than traditional medications.
According to the study above, chronic pain was the second most prevalent reason people used CBG, and 73.9% of them said it relieved their pain better than prescription drugs. Pain that lasts for three months or longer is considered chronic. About 51.6 million Americans, or one in five adult U.S. citizens, suffer from this kind of illness.
Huntington's disease causes the brain's nerve cells to die down. Cannabigerol shields some cells (N2a cells) from excitatory neurotransmitters, which can be harmful if activated for extended periods and result in cell death. Cannabigerol also has a beneficial effect on cell viability.
A 2021 meta-analysis conveys that CBG appears to not only prevent breast cancer cells from increasing in number but may also eliminate inflammatory cells associated with this type of cancer.
According to a 2020 study on cannabis's potential as an antibiotic, CBG shows antibacterial qualities, particularly against Staphylococcus aureus strains that are immune to methicillin. Methicillin-resistant Staphylococcus aureus, and MRSA, is a type of drug-resistant bacteria that causes staph infections.
How is CBG Consumed?
The most common form of commercially available CBG is petroleum, but it is rare and expensive. Alternatively, broad-spectrum CBD oils contain almost all of the cannabinoids found in cannabis.
Medical Marijuana in India: Broad-spectrum CBD oils also contain mixtures called terpenes, which are responsible for the plant's odor and are found in many plants, including fruits and herbs. Using cannabinoids along with terpenes is said to increase their combined effectiveness through a phenomenon named the entourage effect.
Some people consume CBG by smoking cannabis. While this is one way to ingest CBG, cannabis addiction is possible. It is classified as a cannabis use disorder and can negatively affect your biological and mental health while damaging your personal and social relationships.
For information about local support and treatment options, call the Mental Health Services Administration (SAMHSA) and Substance Abuse nationwide helpline at 1-800-662-4357 if you or a loved one is experiencing drug use or addiction.
CBG vs CBD
CBG shares many similarities with CBD:
- Both impact the endocannabinoid system.
- Because none of them are psychoactive, users do not experience a "high."
- All of them are able to offset the intoxicating effects of THC.
One of cannabis plants' main distinctions is the frequency with which CBD and CBG are found. Most cannabis plants only have 1% CBG. In contrast, their CBD level is much higher. Some research indicates that CBD is the second most abundant compound found in these plants—a diversity of molecular targets and signaling pathways of CBD.
CBG also interacts differently with the endocannabinoid method than CBD. CBG binds directly to CB1, Recept CBG oil, and CB2 receptors and could deliver its benefits to the system more efficiently.
Potential Risks of CBG
Currently, CBG products are not regulated by the Food and Drug Administration (FDA). Third-party testing is crucial to ensure product safety and accurate labeling. The results should be easily accessible on the company's website, along with the product's certificate of analysis (COA).
Dr. Sexton says CBG is generally considered safe as long as what you consume is Actually what is advertised. As mentioned, the lack of regulation means it's important to do your homework before purchasing CBG products. Anyone with underlying health conditions or taking supplements or medications should speak with a healthcare provider before trying any product containing CBG.