When it comes to managing pain, medications like Paracetamol and Aceclofenac are commonly used worldwide. While both are effective for relieving pain, they work differently in the body and are prescribed for different types of discomfort. This educational comparison will help you understand the differences, uses, dosage, and safety considerations of these two medications, empowering you to make informed decisions under medical guidance.
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What is Paracetamol?
Paracetamol, also known as acetaminophen, is a widely used pain reliever and fever reducer. It is commonly found in both prescription and over-the-counter formulations. Its primary mechanism of action involves obstructing the brain's chemical messengers that convey heat and pain. Unlike nonsteroidal anti-inflammatory drugs (NSAIDs), paracetamol does not significantly reduce inflammation, which makes it a safer option for people with sensitive stomachs or those who cannot tolerate NSAIDs. Check out the best THC gummies India available online.
Key uses of paracetamol include:
- Headaches and migraines
- Fever reduction
- Mild to moderate body pain
- Joint pain and muscle aches
Advantages of Paracetamol:
- Well-tolerated with minimal gastrointestinal side effects
- Safe for most age groups when used at recommended doses
- Can be combined with other medications, including Aceclofenac, for enhanced pain relief
Maximum dose: Typically, the recommended adult dose is up to 4 grams per day, but this should not be exceeded due to potential liver toxicity.
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What is Aceclofenac?

Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) utilized to cure inflammation and agony brought on by diseases like arthritis, muscle pain, and joint disorders. Unlike paracetamol, Aceclofenac directly targets inflammation, making it effective for conditions where swelling and tenderness accompany pain.
Key uses of Aceclofenac include:
- Osteoarthritis and rheumatoid arthritis
- Ankylosing spondylitis
- Muscle and joint pain
- Postoperative pain management
Advantages of Aceclofenac:
- Provides strong anti-inflammatory action
- Can be used in combination with paracetamol for enhanced pain relief
- Generally well-tolerated and less likely than some other NSAIDs to irritate the gastrointestinal tract
Maximum dose: The usual adult dose of Aceclofenac is 100 mg twice daily, and it should not exceed 200 mg per day.
Paracetamol vs Aceclofenac: Key Differences
You can use these two drugs safely and efficiently if you are aware of their distinctions.
|
Drug Type
|
Analgesic & Antipyretic | NSAID (Nonsteroidal Anti-Inflammatory Drug) |
|
Mechanism of Action
|
Blocks pain and fever signals in the brain | Reduces inflammation and pain by inhibiting COX enzymes |
|
Primary Use
|
Mild to moderate pain, fever | Pain with inflammation (arthritis, joint pain) |
|
Effect on Inflammation
|
Minimal | Significant |
|
Typical Dose
|
500–1000 mg every 4–6 hours (max 4 g/day) | 100 mg twice daily (max 200 mg/day) |
|
Combination Use
|
Can be combined with Aceclofenac | Can be combined with Paracetamol for enhanced relief |
|
Side Effects
|
Rare, mainly liver issues at high doses | Gastrointestinal irritation, rarely liver or kidney issues |
Aceclofenac and Paracetamol Use: When Are They Prescribed Together?

Sometimes, doctors prescribe paracetamol with Aceclofenac to maximize pain relief while minimizing side effects. This combination can be particularly useful in cases of:
- Severe joint pain
- Muscle injuries
- Arthritis flare-ups
- Headaches with inflammatory causes
When taken together, the analgesic effects of paracetamol complement the anti-inflammatory effects of Aceclofenac. This is often available as a combined tablet, sometimes labeled as paracetamol + aceclofenac or aceclofenac and paracetamol tablet for headache.
Important: Always follow the recommended dose of aceclofenac + paracetamol and consult your doctor before using this combination, especially if you have liver, kidney, or stomach issues.
How to Take Aceclofenac and Paracetamol Safely
- Follow the Prescription: Only use Aceclofenac and Paracetamol as prescribed by your doctor. Avoid self-medicating.
- Check the Dose: Do not exceed the aceclofenac maximum dose per day (200 mg) or the paracetamol maximum dose per day (4 g).
- Timing Matters: Some doctors recommend alternating doses if both medications are needed frequently.
- Food Intake: Take Aceclofenac with food to reduce the risk of stomach irritation. Paracetamol can be taken with or without food.
- Hydration: To assist your kidneys, stay hydrated and liver health while taking these medications.
Aceclofenac vs Paracetamol: Which One Should You Use?
The choice between aceclofenac vs paracetamol depends on the type and severity of pain:
- Paracetamol: Best for mild pain and fever without inflammation. Safe for most adults and children when used correctly.
- Aceclofenac: Ideal for pain associated with inflammation, such as arthritis or muscle injuries. Should be used with caution in patients with stomach, kidney, or heart conditions.
- Combination Therapy: Sometimes, the use of paracetamol with aceclofenac offers the best of both worlds—pain relief and inflammation reduction.
Aceclofenac and Paracetamol Tablet for Headache

For headaches, especially those accompanied by muscle tension or inflammation, aceclofenac paracetamol tablets are commonly prescribed. The combination leverages the analgesic effect of paracetamol and the anti-inflammatory effect of Aceclofenac to provide faster and longer-lasting relief.
Dosage: Typically, one tablet of paracetamol+aceclofenac is taken twice daily or as recommended by your doctor. Always avoid exceeding the recommended daily dose to prevent side effects.
PCM Aceclofenac: A Quick Overview
PCM Aceclofenac is another way of referring to a combination of paracetamol (PCM) + Aceclofenac, commonly used in tablets for:
- Arthritis pain
- Muscle aches
- Joint inflammation
- Fever with body pain
The combination is generally safe for adults when taken according to medical guidance.
What Is the Use of Aceclofenac & Paracetamol?
The use of aceclofenac and paracetamol includes managing:
- Mild to moderate pain
- Headaches and migraines
- Muscle and joint inflammation
- Fever and body aches
- Postoperative pain
This combination provides both analgesic and anti-inflammatory benefits, making it more versatile than either drug alone.
Aceclofenac + Paracetamol Dose for Adults
For adult patients, the recommended dose is generally:
- Aceclofenac: 100 mg twice daily
- Paracetamol: 500–1000 mg every 6–8 hours (not exceeding 4 g/day)
- Combination tablet: Typically taken once or twice daily, depending on the formulation and severity of pain
Before beginning any medicine, always get medical advice to ensure safety.
Side Effects of Paracetamol and Aceclofenac
While generally safe, both medications can have side effects if misused.
Paracetamol side effects:
- Rare liver damage at high doses
- Allergic reactions (rash, itching) in sensitive individuals
Aceclofenac side effects:
- Stomach upset or irritation
- Nausea and vomiting
- Rare liver or kidney issues
- Increased risk of heart problems with long-term use
Combination precautions:
- Monitor total paracetamol intake to avoid liver toxicity
- Take Aceclofenac with food to reduce stomach irritation
- Avoid prolonged use without medical supervision
Conclusion
Paracetamol and Aceclofenac are effective pain relievers but serve different purposes. Paracetamol is ideal for mild pain and fever, while Aceclofenac targets pain with inflammation. For many patients, combination therapy (paracetamol + aceclofenac) offers optimal relief for conditions like arthritis, headaches, and muscle pain.
Understanding the differences, dosages, and safe use of these medications ensures effective pain management without unnecessary side effects. Always speak with your doctor before beginning or combining these medications to ensure safety, especially for long-term use.
By using this educational comparison of Paracetamol vs Aceclofenac, patients and caregivers can make informed decisions and improve their overall pain management strategy.
FAQs
Q1: Can I take Paracetamol and Aceclofenac together?
Under medical supervision, they can indeed be taken together. This combination helps manage both pain and inflammation effectively.
Q2: What is the maximum dose of Aceclofenac per day?
The maximum recommended adult dose of Aceclofenac is 200 mg per day.
Q3: Is Paracetamol safe for long-term use?
Paracetamol is generally safe when used at recommended doses, but prolonged high doses can cause liver damage.
Q4: Can Aceclofenac be taken for headaches?
Yes, especially if the headache is associated with inflammation or muscle tension. Combination tablets with paracetamol are commonly used.
Q5: What is PCM Aceclofenac?
PCM Aceclofenac is a combination of paracetamol (PCM) and Aceclofenac used to treat pain and inflammation.
Q6: Can I take Aceclofenac if I have stomach problems?
Caution is advised. Aceclofenac can irritate the stomach, so it should be taken with food and under doctor supervision.